Application:

It can introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as alcohols, carboxylic acids, amines etc… Hence used is in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin. So HMDS/HMDZ is used to produce API like Gemcitabine, Cefprozil, Analapril melate, Efavirenz, Sofosbuvir etc

Ready-to-use preparations for surface treatment of silicon Promotes photoresist adhesion on silicon and SiO2 films Prevents lift-off at edges of photoresist and reduces undercutting.